Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.30 |
| ▸ | POLRMT | O00411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23673324 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL18605958 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL17712322 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL18640705 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL20135843 | 1.00 | TMPRSS2 (0.40) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL17760463 | 0.93 | TMPRSS2 (0.40) | TMPRSS2POLRMT | |
| SCHEMBL20135847 | 0.90 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL20135845 | 0.90 | TMPRSS2 (0.44) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL17712321 | 0.88 | TMPRSS2 (0.39) | TMPRSS2RIPK1 | |
| SCHEMBL23711118 | 0.87 | TMPRSS2 (0.42) | TMPRSS2RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618929-A1 | CRYSTALLINE FORMS OF (S) 2 ETHYLBUTYL 2 (((S) (((2R,3S,4R,5R) 5 (4 AMINOPYRROLO[2,1-F][1,2,4]TRIAZIN-7-YL)-5-CYANO-3,4-DIHYDROXYTETRAHYDROFURAN-2 YL)METHOXY)(PHENOXY) PHOSPHORYL)AMINO)PROPANOATE | Gilead Sciences, Inc. (US) | 2020-03-11 | — | — | EP | disclosed |
| WO-2018204198-A1 | CRYSTALLINE FORMS OF (S) 2 ETHYLBUTYL 2 (((S) (((2R,3S,4R,5R) 5 (4 AMINOPYRROLO[2,1-F] [1,2,4]TRIAZIN-7-YL)-5-CYANO-3,4-DIHYDROXYTETRAHYDROFURAN-2 YL)METHOXY)(PHENOXY) PHOSPHORYL)AMINO)PROPANOATE | GILEAD SCIENCES, INC. (US) | 2018-11-08 | — | — | WO | disclosed |