SCHEMBL20135978

SCHEMBL20135978

COc1cc2cc(C(C)=O)[nH]c2cc1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.55
SRD5A1 P18405 1/20 0.55
SRD5A2 P31213 1/20 0.55
EHMT2 Q96KQ7 1/20 0.53
KMT2A Q03164 8/20 0.52
MEN1 O00255 6/20 0.52
POLB P06746 5/20 0.50
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46
GRIN2D O15399 1/20 0.46
GRIN3B O60391 1/20 0.46
GRIN1 Q05586 1/20 0.46
GRIN2A Q12879 1/20 0.46
GRIN2B Q13224 1/20 0.46
GRIN2C Q14957 1/20 0.46
GRIN3A Q8TCU5 1/20 0.46
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17450307 0.88 GPR35 (0.49) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL16580107 0.87 SRD5A1 (0.54) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL27247640 0.87 KMT2A (0.46) RXFP1SRD5A1SRD5A2KMT2AMEN1
SCHEMBL30920789 0.87 KMT2A (0.46) RXFP1SRD5A1SRD5A2KMT2AMEN1
SCHEMBL335983 0.86 SRD5A1 (0.70) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL6514324 0.84 RXFP1 (0.53) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL15623121 0.84 FLT3 (0.52) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL18900649 0.81 RXFP1 (0.51) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL18900651 0.80 RXFP1 (0.50) RXFP1SRD5A1SRD5A2EHMT2KMT2A
SCHEMBL16795916 0.80 RXFP1 (0.53) RXFP1SRD5A1SRD5A2EHMT2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828269-B1 BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-ALPHA AND/OR BETA COUNCIL SCIENT IND RES (IN) 2018-05-16 EP disclosed
CN-103050629-B A kind of manufacture method of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CENTER (CN) 2016-04-06 CN disclosed
CN-103044390-B Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2015-02-25 CN disclosed
CN-101906093-B Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST MEDICINAL BIOTECHNOLOGY 2013-07-10 CN disclosed
CN-103044389-A Compound used as active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103050628-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103044390-A Manufacturing method of active layer of ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-103050629-A Method for producing ultraviolet detector LIYANG PRODUCTIVITY PROMOTION CT 2013-04-17 CN disclosed
CN-101906093-A Benzo five-membered unsaturated heterocycle compound and preparation method thereof INST OF MEDICINAL BIOTECHNOLOGY OF CHINESE ACADEMY OF MEDICAL SCIENCES 2010-12-08 CN disclosed