⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995326 | 0.83 | — | — | |
| SCHEMBL22788630 | 0.73 | USP2 (0.35) | — | |
| SCHEMBL6445227 | 0.72 | — | — | |
| SCHEMBL28685479 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL29543033 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL30140506 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL11788167 | 0.67 | — | — | |
| SCHEMBL3799284 | 0.67 | — | — | |
| SCHEMBL8443596 | 0.67 | — | — | |
| SCHEMBL9473498 | 0.65 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 838 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026098626-A1 | METHOD FOR PREPARING BENZIMIDAZOLE DERIVATIVE OR SALT THEREOF | 江苏恒瑞医药股份有限公司 | 2026-05-15 | — | — | WO | claimed |
| CN-119119150-B | Icariside II derivative with anti-liver cancer activity and preparation method and application thereof | 沈阳药科大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4558491-A1 | METHODS AND INTERMEDIATES FOR PREPARING 2-[(4-{6-[(4-CYANO-2-FLUOROBENZYL)OXY]PYRIDIN-2-YL}PIPERIDIN-1-YL)METHYL]-1-[(2S)-OXETAN-2-YLMETHYL]-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT | Pfizer Inc. (US) | 2025-05-28 | — | — | EP | claimed |
| CN-119119150-A | Icariside II derivative with anti-liver cancer activity and preparation method and application thereof | 沈阳药科大学 | 2024-12-13 | — | — | CN | claimed |
| CN-118344248-A | 20-Deoxyingenol ether derivative with anti-tumor activity and preparation and application thereof | 沈阳药科大学 | 2024-07-16 | — | — | CN | claimed |
| WO-2024018395-A1 | METHODS AND INTERMEDIATES FOR PREPARING 2-[(4-{6-[(4-CYANO-2-FLUOROBENZYL)OXY]PYRIDIN-2-YL}PIPERIDIN-1-YL)METHYL]-1-[(2S)-OXETAN-2-YLMETHYL]-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT | PFIZER INC. (US) | 2024-01-25 | — | — | WO | claimed |
| CN-116854704-A | Daphnane diterpenoid derivative with anti-liver cancer activity and preparation method and application thereof | 沈阳药科大学 | 2023-10-10 | — | — | CN | claimed |
| CN-115819282-A | Optimization method for preparing 2-chloro-1,1,1-trimethoxyethane | 海门瑞一医药科技有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-105367391-B | A kind of preparation method of the trimethoxy-ethane of 2 chlorine 1,1,1 | 新乡科信化工有限公司 | 2017-07-11 | — | — | CN | claimed |
| EP-2157085-B1 | Oxazole, derivatives of tetracyclines | WYETH LLC (US) | 2011-09-21 | — | — | EP | claimed |
| JP-2007515411-A | — | — | 2007-06-14 | — | — | JP | claimed |
| CN-1890226-A | Oxazole derivatives of tetracyclines | WYETH CORP (US) | 2007-01-03 | — | — | CN | claimed |
| EP-1692117-A1 | OXAZOLE DERIVATIVES OF TETRACYCLINES | Wyeth (US) | 2006-08-23 | — | — | EP | claimed |
| EP-1569925-A1 | 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2005-09-07 | — | — | EP | claimed |
| US-20050153944-A1 | For example, (6aR,7aS,8S,11aS)-5,8-bis(dimethylamino)-2-(2,2-diphenylvinyl)-9,11a,12-trihydroxy-11,13-dioxo-6,6a,7,7a,8,11,11a,13-octahydrotetraceno[2,1-d][1,3]oxazole-10-carboxamide; useful against antibiotic resistant organisms | WYETH (US) | 2005-07-14 | — | — | US | claimed |
| WO-2005056538-A1 | OXAZOLE DERIVATIVES OF TETRACYCLINES | WYETH (US) | 2005-06-23 | — | — | WO | claimed |
| WO-2004055003-A1 | 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | claimed |
| US-20020010371-A1 | Process for preparing a cyclic amino acid anticonvulsant compound | DEERING CARL FRANCIS (US) | 2002-01-24 | — | — | US | claimed |
| US-6294690-B1 | REACTING BENZONITRILE WITH ALKALI METAL IN AMMONIA OR AMINE IN SOLVENT TO FORM ANIONIC INTERMEDIATE, ALKYLATING WITH HALOACETIC ACID, HYDROGENATING RING, HYDROGENATING NITRILE TO AMINE TO PRODUCE GABAPENTIN | WARNER-LAMBERT COMPANY | 2001-09-25 | — | — | US | claimed |
| WO-1999018063-A2 | PROCESS FOR PREPARING A CYCLIC AMINO ACID ANTICONVULSANT COMPOUND | WARNER-LAMBERT COMPANY (US) | 1999-04-15 | — | — | WO | claimed |