SCHEMBL20137398

SCHEMBL20137398

C/C=C/C=C/C(=O)OCCCC[SiH](OC)OC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 4/20 0.39
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 2/20 0.34
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.32
APP P05067 4/20 0.31
PRKCA P17252 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150923 0.89 ATM (0.44) ATMHCAR2LMNAHTTALDH1A1
SCHEMBL297601 0.83 ATM (0.46) ATMHCAR2LMNAALDH1A1TSHR
SCHEMBL30026607 0.83 ATM (0.52) ATMHCAR2LMNAMAPK1HTT
SCHEMBL12462153 0.81 ATM (0.54) ATMHCAR2LMNAMAPK1HTT
SCHEMBL9156392 0.78 HCAR2 (0.62) ATMHCAR2HTTTSHRMAPT
SCHEMBL9398156 0.78 ATM (0.47) ATMHCAR2LMNAMAPK1HTT
SCHEMBL9398160 0.78 ATM (0.47) ATMHCAR2LMNAMAPK1HTT
SCHEMBL28214424 0.78 ATM (0.41) ATMHCAR2ALDH1A1TSHRCYP3A4
SCHEMBL10411264 0.77 ATM (0.46) ATMHCAR2LMNAMAPK1HTT
SCHEMBL18173795 0.77 ATM (0.46) ATMHCAR2LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
EP-3310793-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-06-09 EP claimed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN claimed
US-10273254-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-30 US claimed
US-10246473-B2 Process for preparing an acryloyloxysilane DOW CORNING CORPORATION (US) 2019-04-02 US claimed
US-20180155371-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-06-07 US claimed
US-20180134734-A1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORPORATION 2018-05-17 US claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP disclosed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN disclosed