Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631751 | 0.78 | HRH1 (0.30) | — | |
| SCHEMBL28654885 | 0.76 | PDE4A (0.50) | HTR2CPIN1PDE4APDE4BPDE4C | |
| SCHEMBL12343963 | 0.74 | ADORA2A (0.37) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5439409 | 0.74 | CYP2A6 (0.35) | — | |
| SCHEMBL27374635 | 0.73 | HTR2C (0.49) | HTR2CPIN1PDE4APDE4BPDE4C | |
| SCHEMBL30918003 | 0.73 | HTR2C (0.49) | HTR2CPIN1PDE4APDE4BPDE4C | |
| SCHEMBL14964889 | 0.71 | HRH3 (0.39) | TDP1L3MBTL1 | |
| SCHEMBL19838265 | 0.70 | — | — | |
| SCHEMBL14965474 | 0.69 | ADORA2A (0.51) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19714623 | 0.68 | HTR2C (0.48) | HTR2CPIN1NOS1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |