Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918003 | 1.00 | HTR2C (0.49) | HTR2CPIN1NPC1RAB9AKCNH2 | |
| SCHEMBL27372800 | 0.89 | HTR2C (0.49) | HTR2CPIN1SMN1; SMN2HTTSTAT3 | |
| SCHEMBL28206527 | 0.86 | KMT2A (0.39) | HTR2CPIN1NPC1RAB9AKCNH2 | |
| SCHEMBL3049083 | 0.83 | L3MBTL1 (0.47) | HTR2CPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28206083 | 0.80 | HTR2C (0.43) | HTR2CPIN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28206532 | 0.80 | TLR8 (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9971271 | 0.79 | KDM4E (0.44) | KDM4EGPR3EGFR | |
| SCHEMBL6665065 | 0.79 | LOXL2 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EGPR3 | |
| SCHEMBL30553021 | 0.79 | KDM4E (0.39) | NPC1KDM4EGPR3EGFR | |
| SCHEMBL5741619 | 0.79 | KDM4E (0.39) | NPC1KDM4EGPR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831610-B | A kind of catalysis oxidation synthetic method of quinazoline compounds | 浙江工业大学 | 2019-03-19 | — | — | CN | disclosed |
| CN-107372522-A | A kind of composition pesticide containing fenazaquin | 江西正邦生物化工有限责任公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-106831610-A | A kind of catalysis oxidation synthetic method of quinazoline compounds | 浙江工业大学 | 2017-06-13 | — | — | CN | disclosed |
| CN-104364237-B | Histone deacetylase (HDACS) inhibitors | 安基生技新药股份有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-1329493-A | Methods and compositions for restoring conformational stability of proteins of the p53 family | PFIZER PROD INC (US) | 2002-01-02 | — | — | CN | disclosed |
| CN-1052379-C | Quinazoline derisatives | DOWELANCO (US) | 2000-05-17 | — | — | CN | disclosed |