Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159435 | 1.00 | ROCK2 (0.54) | ROCK2NAMPT | |
| SCHEMBL20139021 | 1.00 | ROCK2 (0.54) | ROCK2NAMPT | |
| SCHEMBL20138893 | 0.93 | NAMPT (0.52) | NAMPT | |
| SCHEMBL20159173 | 0.89 | NAMPT (0.56) | NAMPT | |
| SCHEMBL20138894 | 0.89 | NAMPT (0.56) | NAMPT | |
| SCHEMBL20159465 | 0.89 | NAMPT (0.56) | NAMPT | |
| SCHEMBL20138896 | 0.88 | NAMPT (0.54) | NAMPT | |
| SCHEMBL20159445 | 0.88 | NAMPT (0.55) | NAMPT | |
| SCHEMBL20159581 | 0.88 | HDAC2 (0.43) | ROCK2NAMPT | |
| SCHEMBL20159459 | 0.88 | NAMPT (0.53) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |