Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.59 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15006962 | 1.00 | GPR119 (0.59) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL16236440 | 1.00 | GPR119 (0.59) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL23560775 | 0.87 | GPR119 (0.62) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL1448170 | 0.87 | GPR119 (0.65) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL12740835 | 0.87 | GPR119 (0.65) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL1448169 | 0.87 | GPR119 (0.65) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL23560705 | 0.86 | GPR119 (0.61) | GPR119GRM1MAP4K4HDAC1MAPT | |
| SCHEMBL1448124 | 0.86 | GPR119 (0.61) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL23560974 | 0.86 | GPR119 (0.61) | GPR119GRM1MAP4K4SLC6A7HDAC1 | |
| SCHEMBL12740848 | 0.86 | GPR119 (0.61) | GPR119GRM1MAP4K4SLC6A7HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665331-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173219-A1 | ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-08-22 | — | — | WO | disclosed |
| WO-2021123291-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |