Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28280817 | 0.85 | KDM4E (0.59) | FOLH1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL10383765 | 0.80 | FOLH1 (0.71) | FOLH1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28660747 | 0.80 | MEN1 (0.43) | FOLH1ALDH1A1MAPK1STAT3KDM4E | |
| SCHEMBL14119038 | 0.79 | MEN1 (0.46) | FOLH1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL20140769 | 0.79 | FOLH1 (0.48) | FOLH1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL2272671 | 0.76 | MEN1 (0.62) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL28660724 | 0.75 | MEN1 (0.45) | FOLH1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL28659959 | 0.73 | MEN1 (0.44) | FOLH1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL28665614 | 0.72 | MEN1 (0.44) | FOLH1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL28662112 | 0.72 | MEN1 (0.43) | FOLH1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |