Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.38 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274832 | 0.85 | KDM4E (0.44) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL316590 | 0.84 | KDM4E (0.40) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL20141358 | 0.82 | KDM4E (0.41) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL27449011 | 0.80 | TPMT (0.48) | KDM4EMEN1KMT2ATDP1TPMT | |
| SCHEMBL27411185 | 0.79 | KDM4E (0.54) | KDM4EMEN1KMT2ATDP1HMGB1 | |
| SCHEMBL13199299 | 0.79 | PDCD1 (0.41) | KDM4ECSNK2A1GABRPGABRDGABRA1 | |
| SCHEMBL28324640 | 0.77 | HMGB1 (0.45) | HMGB1CXCL12GABRPGABRDGABRA1 | |
| SCHEMBL18541219 | 0.77 | SHBG (0.39) | KDM4EMEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL27952126 | 0.76 | SMN1; SMN2 (0.46) | KDM4ETDP1HPGDHSD17B10CA12 | |
| SCHEMBL13199185 | 0.75 | NPSR1 (0.41) | KDM4EHMGB1CXCL12TPMTCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |