Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 18/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139868 | 0.86 | MTOR (0.52) | MTORRPTORMLST8 | |
| SCHEMBL20140818 | 0.82 | P2RX7 (0.46) | P2RX7MTORRPTORMLST8 | |
| SCHEMBL20141373 | 0.81 | MTOR (0.49) | P2RX7MTORRPTORMLST8 | |
| SCHEMBL20140694 | 0.78 | MTOR (0.50) | MTORRPTORMLST8 | |
| SCHEMBL20139945 | 0.77 | MTOR (0.49) | P2RX7MTORRPTORMLST8 | |
| SCHEMBL13197677 | 0.76 | NOTUM (0.47) | P2RX7 | |
| SCHEMBL30280978 | 0.76 | FASN (0.52) | — | |
| SCHEMBL20139861 | 0.75 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL20139970 | 0.74 | GRM1 (0.39) | MTORRPTORMLST8 | |
| SCHEMBL20139990 | 0.74 | MTOR (0.40) | MTORRPTORMLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |