Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.60 |
| ▸ | CCR5 | P51681 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139701 | 0.86 | RORC (0.65) | RORCCCR5GBA1PAX8 | |
| SCHEMBL20139698 | 0.86 | RORC (0.65) | RORCCCR5GBA1PAX8 | |
| SCHEMBL20140255 | 0.75 | RORC (1.00) | RORCCCR5DRD2DRD3GBA1 | |
| SCHEMBL20140253 | 0.75 | RORC (1.00) | RORCCCR5DRD2DRD3GBA1 | |
| SCHEMBL23683609 | 0.74 | RORC (0.60) | RORCCCR5 | |
| SCHEMBL20139553 | 0.74 | RORC (0.60) | RORCCCR5 | |
| SCHEMBL31412702 | 0.73 | GBA1 (0.52) | RORCCCR5DRD2DRD3GBA1 | |
| SCHEMBL1439367 | 0.72 | RORC (0.49) | RORCCCR5DRD2DRD3GBA1 | |
| SCHEMBL1439546 | 0.72 | RORC (0.49) | RORCCCR5DRD2DRD3GBA1 | |
| SCHEMBL1937578 | 0.72 | RORC (0.49) | RORCCCR5DRD2DRD3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538522-A1 | ROR GAMMA MODULATORS | Bristol-Myers Squibb Company (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |