Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.46 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.46 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139969 | 0.84 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140827 | 0.84 | MTOR (0.51) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20156928 | 0.82 | MTOR (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20141458 | 0.81 | MTOR (0.65) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20141002 | 0.80 | MCL1 (0.46) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20156930 | 0.79 | MTOR (0.46) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20142111 | 0.76 | MTOR (0.57) | MTORRPTORMLST8ALDH1A1GFER | |
| SCHEMBL20140606 | 0.76 | MTOR (0.44) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20141464 | 0.76 | MTOR (0.56) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140576 | 0.75 | MTOR (0.48) | MTORRPTORMLST8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |