Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139936 | 0.84 | MTOR (0.46) | MTORRPTORMLST8HTTGAA | |
| SCHEMBL20141897 | 0.83 | HTT (0.47) | HTTGAATSHRKDM4EALDH1A1 | |
| SCHEMBL20156964 | 0.83 | MTOR (0.49) | MTORRPTORMLST8HTTKDM4E | |
| SCHEMBL20157489 | 0.82 | MTOR (0.49) | MTORRPTORMLST8HTTKDM4E | |
| SCHEMBL20140827 | 0.82 | MTOR (0.51) | MTORRPTORMLST8HTTGAA | |
| SCHEMBL20141707 | 0.80 | MTOR (0.47) | MTORRPTORMLST8KDM4EPARP1 | |
| SCHEMBL20139934 | 0.80 | PPARG (0.47) | MTORRPTORMLST8HTTKDM4E | |
| SCHEMBL20141892 | 0.80 | PKM (0.47) | GAATSHRKDM4EALDH1A1TNF | |
| SCHEMBL20141002 | 0.79 | MCL1 (0.46) | MTORRPTORMLST8HTTGAA | |
| SCHEMBL20157050 | 0.78 | MTOR (0.55) | MTORRPTORMLST8HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |