Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140768 | 0.87 | DRD4 (0.50) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20140551 | 0.85 | MTOR (0.52) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20140723 | 0.82 | P2RY12 (0.49) | DRD3KDM4EALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL20139948 | 0.79 | DRD4 (0.48) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20140750 | 0.77 | DRD4 (0.48) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20140616 | 0.76 | DRD4 (0.45) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20141552 | 0.76 | DRD4 (0.47) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20140738 | 0.76 | MTOR (0.54) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20139999 | 0.73 | DRD4 (0.48) | DRD4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL20140641 | 0.73 | MTOR (0.54) | DRD4DRD2DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |