Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140641 | 0.88 | MTOR (0.54) | KDM4EALDH1A1LMNAMTORRPTOR | |
| SCHEMBL20139973 | 0.86 | MTOR (0.57) | KDM4EALDH1A1MEN1KMT2AMTOR | |
| SCHEMBL20139984 | 0.82 | DRD4 (0.46) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL20140146 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1TDP1MTORRPTOR | |
| SCHEMBL20140097 | 0.79 | MTOR (0.51) | KDM4EALDH1A1LMNAMTORRPTOR | |
| SCHEMBL20140083 | 0.78 | MTOR (0.49) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL20157267 | 0.77 | DRD4 (0.52) | KDM4EALDH1A1LMNAMTORRPTOR | |
| SCHEMBL20140388 | 0.77 | MTOR (0.47) | MTORRPTORMLST8DRD3 | |
| SCHEMBL20156883 | 0.75 | MTOR (0.46) | KDM4EALDH1A1MAPTHSD17B10LMNA | |
| SCHEMBL20140126 | 0.75 | MTOR (0.53) | KDM4EALDH1A1LMNAMTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |