Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 4/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140002 | 1.00 | CHRM4 (0.40) | CHRM4PPARGGRM1CHRM1HDAC1 | |
| SCHEMBL20140780 | 0.82 | CHRM4 (0.42) | CHRM4PPARGGRM1CHRM1HDAC1 | |
| SCHEMBL20140046 | 0.79 | MTOR (0.47) | CHRM4PPARGGRM1CHRM1MTOR | |
| SCHEMBL20140048 | 0.79 | MTOR (0.47) | CHRM4PPARGGRM1CHRM1MTOR | |
| SCHEMBL20140070 | 0.79 | MTOR (0.47) | CHRM4PPARGGRM1CHRM1MTOR | |
| SCHEMBL20140732 | 0.78 | CHRM1 (0.47) | CHRM4PPARGGRM1CHRM1HDAC1 | |
| SCHEMBL20157507 | 0.78 | CHRM1 (0.47) | CHRM4PPARGGRM1CHRM1HDAC1 | |
| SCHEMBL20139350 | 0.77 | MTOR (0.47) | CHRM4MTORRPTORMLST8KMT2A | |
| SCHEMBL20139349 | 0.77 | MTOR (0.47) | CHRM4MTORRPTORMLST8KMT2A | |
| Trifluoroacetic Acid SCHEMBL20141565 | 0.76 | CHRM4 (0.45) | CHRM4PPARGGRM1CHRM1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |