Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977592 | 0.92 | ALDH1A1 (0.63) | ALDH1A1MAPTLMNAKCNH2MEN1 | |
| SCHEMBL2973720 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL31220479 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAKCNH2MEN1 | |
| SCHEMBL27432559 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAKCNH2MEN1 | |
| SCHEMBL2969622 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAKCNH2MEN1 | |
| SCHEMBL4435451 | 0.82 | MAPT (0.63) | ALDH1A1MAPTLMNAKMT2AMET | |
| SCHEMBL30998112 | 0.82 | MAPT (0.63) | ALDH1A1MAPTLMNAKMT2AMET | |
| SCHEMBL1063164 | 0.81 | MAPT (0.52) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1247295 | 0.81 | MAPT (0.59) | ALDH1A1MAPTLMNAKCNH2MEN1 | |
| SCHEMBL29608605 | 0.80 | MAPT (0.58) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |