Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366827 | 0.88 | NPSR1 (0.45) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL28043598 | 0.88 | NPSR1 (0.45) | NPSR1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL23673380 | 0.86 | NPSR1 (0.44) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL31586538 | 0.86 | NPSR1 (0.44) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL19028097 | 0.85 | NPSR1 (0.42) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL30083653 | 0.85 | NPSR1 (0.42) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL31214243 | 0.82 | CFTR (0.41) | NPSR1ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL21679244 | 0.82 | NPSR1 (0.40) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL31586448 | 0.81 | NPSR1 (0.39) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E | |
| SCHEMBL31586781 | 0.81 | NPSR1 (0.39) | NPSR1KEAP1NFE2L2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |