Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | DRD3 | P35462 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139944 | 0.87 | DRD4 (0.52) | GPR6DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL20157267 | 0.82 | DRD4 (0.52) | GPR6DRD4DRD2DRD3ALDH1A1 | |
| SCHEMBL20140542 | 0.74 | DRD4 (0.50) | DRD4DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL18997917 | 0.74 | KDM4E (0.43) | DRD4DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL19002713 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP1A2LMNA | |
| SCHEMBL20139948 | 0.72 | DRD4 (0.48) | DRD4DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL16954479 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KDM4ECYP1A2LMNA | |
| SCHEMBL4520079 | 0.72 | ALDH1A1 (0.68) | DRD4DRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL28746194 | 0.72 | ALDH1A1 (0.68) | ALDH1A1KDM4ELMNAHTR7 | |
| SCHEMBL20140126 | 0.72 | MTOR (0.53) | DRD4DRD2DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |