Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141175 | 0.90 | ALDH1A1 (0.45) | ALDH1A1LMNAHTR2CUSP28USP25 | |
| SCHEMBL12182701 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNACHRM2HTR2CALK | |
| SCHEMBL12182668 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNACHRM2HTR2CALK | |
| Hydrochloric Acid SCHEMBL29767487 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNACHRM2HTR2CALK | |
| Hydrochloric Acid SCHEMBL28829934 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNACHRM2HTR2CALK | |
| Hydrochloric Acid SCHEMBL28829935 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNACHRM2HTR2CALK | |
| SCHEMBL20159179 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAHTR2CKCNH2HRH3 | |
| SCHEMBL18825914 | 0.80 | KHK (0.46) | ALDH1A1CHRM2KCNH2MAPTBCL2A1 | |
| SCHEMBL8295259 | 0.79 | ALDH1A1 (0.75) | ALDH1A1LMNAUSP28USP25TRPV4 | |
| SCHEMBL30073656 | 0.79 | ALDH1A1 (0.75) | ALDH1A1LMNAUSP28USP25TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |