Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324883 | 0.83 | LCK (0.39) | LCKAAK1ARCYP2C9CYP2C19 | |
| SCHEMBL13548419 | 0.82 | CYP2C9 (0.46) | LCKARCYP2C9CYP2C19NPSR1 | |
| SCHEMBL24296963 | 0.80 | CYP2C9 (0.43) | LCKAAK1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL1229320 | 0.80 | KDM4E (0.43) | KDM4EPKMHSD17B10MAPT | |
| SCHEMBL277358 | 0.79 | AAK1 (0.43) | LCKAAK1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL1605808 | 0.79 | MAPT (0.43) | AAK1ARCYP2C9CYP2C19NPSR1 | |
| SCHEMBL28652107 | 0.79 | KDM4E (0.36) | KDM4EPKMHSD17B10MAPT | |
| SCHEMBL8055911 | 0.76 | AKR1C4 (0.55) | LCKARCYP2C9KDM4EHSD17B10 | |
| SCHEMBL31668173 | 0.76 | AKR1C4 (0.55) | LCKARCYP2C9KDM4EHSD17B10 | |
| SCHEMBL6350428 | 0.75 | CYP2C9 (0.41) | ARCYP2C9CYP2C19NPSR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |