Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28507481 | 0.85 | HSD17B10 (0.43) | KDM4EHSD17B10MAPTATMHPGD | |
| SCHEMBL28532275 | 0.84 | KDR (0.39) | KDM4EPKMHSD17B10MAPTNPC1 | |
| SCHEMBL1229320 | 0.83 | KDM4E (0.43) | KDM4EPKMHSD17B10MAPTKMT2A | |
| SCHEMBL20140708 | 0.79 | LCK (0.38) | KDM4EPKMHSD17B10MAPT | |
| SCHEMBL28708200 | 0.78 | CYP3A4 (0.35) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL29548189 | 0.76 | AKR1C3 (0.50) | KDM4EHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL1071109 | 0.76 | AKR1C3 (0.50) | KDM4EHSD17B10HPGDMEN1KMT2A | |
| SCHEMBL25994225 | 0.76 | SMN1; SMN2 (0.40) | KDM4EPKMHSD17B10MAPTNPC1 | |
| SCHEMBL27479609 | 0.75 | LOXL2 (0.36) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL1518477 | 0.70 | KMT2A (0.57) | NPC1HPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527275-A | SKLB1039 compound and preparation method and application thereof | 成都师范学院 | 2021-10-22 | — | — | CN | disclosed |