Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205477 | 0.87 | TSHR (0.49) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL2301745 | 0.86 | KDM4E (0.77) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL7598160 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL11470029 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL30531237 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL16387742 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL14459600 | 0.78 | KDM4E (0.71) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL20472390 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL29786432 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1ALOX15TSHRHPGD | |
| SCHEMBL18386312 | 0.77 | CA12 (0.54) | KDM4ETSHRKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |