Sugi Predict

Sugi Predict / Compounds / SCHEMBL2301745

SCHEMBL2301745

SCHEMBL2301745

CCOC(=O)c1cc(C(=O)OCC)c(C)nc1C

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.77
▸ ALDH1A1 P00352 4/20 0.68
▸ ALOX15 P16050 1/20 0.66
▸ HPGD P15428 3/20 0.60
▸ TSHR P16473 2/20 0.59
▸ HSD17B10 Q99714 1/20 0.59
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ GAA P10253 1/20 0.56
▸ KMT2A Q03164 2/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ MAPT P10636 4/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ LMNA P02545 1/20 0.53
▸ POLB P06746 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11470029 0.93 KDM4E (0.69) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL7598160 0.93 KDM4E (0.69) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL30531237 0.93 KDM4E (0.69) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL14459600 0.91 KDM4E (0.71) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL16387742 0.89 KDM4E (0.64) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL20472390 0.87 KDM4E (0.62) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL29786432 0.87 KDM4E (0.62) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL20140713 0.86 KDM4E (0.60) KDM4EALDH1A1ALOX15HPGDTSHR
SCHEMBL346578 0.84 TSHR (0.67) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL4876987 0.83 KDM4E (0.57) KDM4EALDH1A1ALOX15HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108169346-B Gas chromatography-mass spectrometry combined detection method for dihydropyridine in feed 华测检测认证集团股份有限公司 2021-02-02 — — CN claimed
CN-111170905-A Synthetic method of sulfonamide compound 台州学院 2020-05-19 — — CN claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 — — US claimed
US-20250281483-A1 TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF Astellas Engineered Small Molecules US, Incorporated 2025-09-11 — — US disclosed
EP-4511112-A1 TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF Astellas Engineered Small Molecules US, Incorporated (US) 2025-02-26 — — EP disclosed
CN-115626889-B Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound 南京工业大学 2024-04-30 — — CN disclosed
US-20230382749-A1 PHOTODRIVEN TRANSFER HYDROGENATION OF N2 TO NH3 CALIFORNIA INST OF TECHN (US) 2023-11-30 — — US disclosed
US-11813596-B2 Photocatalytic system and applications thereof Max Planck Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-11-14 — — US disclosed
WO-2023205415-A1 TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF MITOBRIDGE INC. (US) 2023-10-26 — — WO disclosed
WO-2023205415-A1 TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF MITOBRIDGE INC. (US) 2023-10-26 — — WO disclosed
US-11731117-B2 Compositions of certain manganese accumulating plants CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-22 — — US disclosed
EP-2349999-A1 ALLOSTERIC PROTEIN KINASE MODULATORS Universität des Saarlandes (DE) 2011-08-03 — — EP disclosed
US-20090163535-A1 Substituted Heteroarylalkanoic Acids THE INSTITUES FOR PHARMACEUTICAL DISCOVERY, INC. (US) 2009-06-25 — — US disclosed
EP-1444228-B1 SUBSTITUTED HETEROARYLALKANOIC ACIDS AND THEIR USE AS ALDOSE REDUCTASE INHIBITORS INST FOR PHARM DISCOVERY INC (US) 2008-05-21 — — EP disclosed
US-7361671-B2 Substituted heteroarylalkanoic acids THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, INC. (US) 2008-04-22 — — US disclosed
EP-1868990-A2 NOVEL HETEROCYCLIC DERIVATIVES Orchid Research Laboratories Limited (IN) 2007-12-26 — — EP disclosed
WO-2006126074-A2 HETEROCYCLIC DERIVATIVES ORCHID RESEARCH LABORATORIES LIMITED (IN) 2006-11-30 — — WO disclosed
WO-2006109146-A2 NOVEL HETEROCYCLIC DERIVATIVES ORCHID RESEARCH LABORATORIES LIMITED (IN) 2006-10-19 — — WO disclosed
US-20030166668-A1 Substituted heteroarylalkanoic acids THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. A CORPORATION OF THE STATE OF DELAWARE 2003-09-04 — — US disclosed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731117-B2 Compositions of certain manganese accumulating plants AS3MT, ME3, CACYBP KDM4E 3775/4885ALDH1A1 3493/4885ALOX15 3393/4885
US-20090163535-A1 Substituted Heteroarylalkanoic Acids GPR119, LIPA, LIPC KDM4E 4022/4885ALDH1A1 227/4885ALOX15 116/4885
US-11813596-B2 Photocatalytic system and applications thereof HCCS, CRY1, PCBP1 KDM4E 2443/4885ALDH1A1 2102/4885ALOX15 2252/4885
US-20030166668-A1 Substituted heteroarylalkanoic acids GPR119, LIPA, DDC KDM4E 4051/4885ALDH1A1 270/4885ALOX15 130/4885
US-20250281483-A1 TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF TFEB, MITF, CREBBP KDM4E 2002/4885ALDH1A1 2399/4885ALOX15 1961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.