Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 2/20 | 0.42 |
| ▸ | PRKACG | P22612 | 2/20 | 0.42 |
| ▸ | PRKACB | P22694 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129660 | 1.00 | HTR2A (0.48) | HTR2AHTR2CHTR2BPRKD3PRKCG | |
| SCHEMBL2419267 | 0.80 | HTR2A (0.53) | HTR2AHTR2CHTR2BGSK3B | |
| SCHEMBL6219727 | 0.80 | HTR2A (0.53) | HTR2AHTR2CHTR2BGSK3B | |
| SCHEMBL13931360 | 0.78 | HTR2C (0.53) | HTR2AHTR2CHTR2B | |
| SCHEMBL20129651 | 0.77 | EPHX2 (0.52) | HTR2CCYP3A4TSHRNFKB1LMNA | |
| SCHEMBL9206909 | 0.75 | HTR2C (0.51) | HTR2AHTR2CHTR2BCYP2C19 | |
| SCHEMBL20141349 | 0.75 | SMO (0.45) | SMN1; SMN2KMT2AMTORHTTLMNA | |
| SCHEMBL3331400 | 0.74 | HTR2C (0.50) | HTR2AHTR2CHTR2BPRKCQALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27277144 | 0.74 | CYP1A2 (0.51) | HTR2AHTR2CHTR2BSMN1; SMN2MAPK1 | |
| SCHEMBL20129734 | 0.73 | PRKCQ (0.45) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |