Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 13/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129661 | 0.86 | SMARCA2 (0.51) | SMOGRM1 | |
| SCHEMBL20141823 | 0.86 | SMARCA2 (0.51) | SMOGRM1 | |
| SCHEMBL20140927 | 0.79 | CA1 (0.47) | KMT2AMTORRPTORMLST8 | |
| SCHEMBL20140997 | 0.77 | GRM1 (0.47) | SMOSLC6A7GRM1 | |
| SCHEMBL20141187 | 0.77 | SMO (0.45) | SMOSLC6A7GRM1SMN1; SMN2KMT2A | |
| SCHEMBL20140940 | 0.75 | HTR2A (0.48) | LMNAHTTSMN1; SMN2KMT2AMTOR | |
| SCHEMBL20129660 | 0.75 | HTR2A (0.48) | LMNAHTTSMN1; SMN2KMT2AMTOR | |
| SCHEMBL20140855 | 0.74 | GRM1 (0.67) | SMOSLC6A7GRM1SMN1; SMN2 | |
| SCHEMBL3119867 | 0.74 | SLC6A7 (0.43) | SMOSLC6A7GRM1SMN1; SMN2 | |
| SCHEMBL6904992 | 0.72 | MAPK1 (0.55) | SLC6A7LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |