Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.58 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.34 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049060 | 1.00 | GRIK1 (0.58) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL2014130 | 1.00 | GRIK1 (0.58) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL9073285 | 0.84 | GRIK1 (0.43) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL7168760 | 0.82 | GRIK1 (0.58) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL4556871 | 0.82 | GRIK1 (0.69) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL4556870 | 0.82 | GRIK1 (0.69) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL25466254 | 0.80 | GRIK1 (0.47) | GRIK1 | |
| SCHEMBL455204 | 0.78 | GRIK1 (0.42) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL3927257 | 0.78 | GRIK1 (0.55) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL7391128 | 0.77 | GRIK1 (0.37) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071520-A1 | PROCESSES FOR THE PREPARATION OF (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | DISSYMMETRIX (PVT) LTD. (IN) | 2011-06-16 | — | — | WO | disclosed |