Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228875 | 0.85 | GRIK1 (0.34) | GRIK1 | |
| SCHEMBL2397898 | 0.83 | GRIK1 (0.52) | GRIK1 | |
| SCHEMBL2397901 | 0.83 | GRIK1 (0.52) | GRIK1 | |
| SCHEMBL2014126 | 0.80 | GRIK1 (0.58) | GRIK1 | |
| SCHEMBL2014130 | 0.80 | GRIK1 (0.58) | GRIK1 | |
| SCHEMBL7049060 | 0.80 | GRIK1 (0.58) | GRIK1 | |
| SCHEMBL14879 | 0.77 | — | — | |
| SCHEMBL2049250 | 0.77 | — | — | |
| SCHEMBL14881 | 0.77 | — | — | |
| Acrylic Acid SCHEMBL31544630 | 0.74 | GRIK1 (0.44) | GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083297-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |