SCHEMBL2014129

SCHEMBL2014129

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nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2331627 0.80
SCHEMBL15167302 0.80
SCHEMBL14739959 0.73
SCHEMBL12375515 0.73 ALDH1A1 (0.39) ALDH1A1ALOX15
SCHEMBL290166 0.73
SCHEMBL17748990 0.73
SCHEMBL23581178 0.71 ALDH1A1 (0.33) ALDH1A1ALOX15
SCHEMBL17505971 0.71 KDM4E (0.31)
SCHEMBL23581176 0.71 ALDH1A1 (0.33) ALDH1A1ALOX15
SCHEMBL694706 0.71 HCAR2 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4083091-B1 POLYMER ELECTROLYTE, AND LITHIUM ION BATTERY COMPRISING SAME ZHUHAI COSMX BATTERY CO LTD (CN) 2024-08-14 EP disclosed
EP-4083091-A1 POLYMER ELECTROLYTE, AND LITHIUM ION BATTERY COMPRISING SAME Zhuhai CosMX Battery Co., Ltd. (CN) 2022-11-02 EP disclosed
US-20220216513-A1 POLYMER ELECTROLYTE AND LITHIUM-ION BATTERY INCLUDING THE POLYMER ELECTROLYTE ZHUHAI COSMX BATTERY CO., LTD. (CN) 2022-07-07 US disclosed
US-20140243290-A1 Aminopyrimidines as SYK Inhibitors ALTMAN MICHAEL D (US) 2014-08-28 US disclosed
US-8759366-B2 Aminopyrimidines as SYK inhibitors MERCK SHARP & DOHME CORP. (US) 2014-06-24 US disclosed
US-8551984-B2 Aminopyrimidines as SYK inhibitors MERCK SHARP & DOHME CORP. (US) 2013-10-08 US disclosed
US-20120277192-A1 AMINOPYRIMIDINES AS SYK INHIBITORS MERCK SHARP & DOHME LLC 2012-11-01 US disclosed
EP-2513098-A1 AMINOPYRIMIDINES AS SYK INHIBITORS Merck Sharp & Dohme Corp. (US) 2012-10-24 EP disclosed
US-20110245205-A1 AMINOPYRIMIDINES AS SYK INHIBITORS MERCK SHARP & DOHME LLC 2011-10-06 US disclosed
WO-2011075515-A1 AMINOPYRIMIDINES AS SYK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245205-A1 AMINOPYRIMIDINES AS SYK INHIBITORS SYK, BTK, LCK ALDH1A1 1614/4885ALOX15 1541/4885
US-20140243290-A1 Aminopyrimidines as SYK Inhibitors SYK, BTK, LCK ALDH1A1 1614/4885ALOX15 1541/4885
US-20120277192-A1 AMINOPYRIMIDINES AS SYK INHIBITORS SYK, BTK, LCK ALDH1A1 1614/4885ALOX15 1541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.