Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719857 | 0.86 | PARP1 (0.37) | MEN1KMT2APKMPOLBL3MBTL1 | |
| SCHEMBL28719855 | 0.86 | PARP1 (0.37) | MEN1KMT2APKMPOLBL3MBTL1 | |
| SCHEMBL20314864 | 0.82 | JAK3 (0.34) | MEN1KMT2APKM | |
| SCHEMBL25839519 | 0.82 | JAK3 (0.34) | MEN1KMT2APKM | |
| SCHEMBL25738592 | 0.79 | PKM (0.33) | PKMPOLBL3MBTL1 | |
| SCHEMBL26551530 | 0.79 | NR1H2 (0.48) | MEN1KMT2AMAPK1L3MBTL1HRH3 | |
| SCHEMBL27031176 | 0.77 | PIK3CD (0.39) | MEN1KMT2ATACR1CHRM3POLB | |
| SCHEMBL27230523 | 0.77 | TACR1 (0.39) | TACR1POLBL3MBTL1PIK3CD | |
| SCHEMBL27209164 | 0.77 | TACR1 (0.39) | TACR1POLBL3MBTL1PIK3CD | |
| SCHEMBL27133377 | 0.77 | PIK3CD (0.39) | MEN1KMT2ATACR1CHRM3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |