Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16031955 | 0.80 | CNR1 (0.43) | CNR1CNR2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL22691771 | 0.79 | CNR1 (0.43) | CNR1CNR2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL22691770 | 0.79 | CNR1 (0.43) | CNR1CNR2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL22690845 | 0.78 | ALDH1A1 (0.42) | CNR1CNR2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL16508612 | 0.76 | IDO1 (0.37) | L3MBTL1CTSAALDH1A1SLC6A9 | |
| SCHEMBL20141442 | 0.75 | HTT (0.43) | CNR1CNR2L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL4251745 | 0.73 | SMN1; SMN2 (0.44) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL67172 | 0.73 | ALDH1A1 (0.48) | L3MBTL1CTSAALDH1A1NPC1RAB9A | |
| SCHEMBL236187 | 0.72 | ALDH1A1 (0.37) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14725902 | 0.71 | IDO1 (0.38) | CTSAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |