Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5514821 | 0.81 | KMT2A (0.48) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL23649245 | 0.80 | TDP1 (0.46) | CYP2C19SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL3005617 | 0.76 | TAAR1 (0.46) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL27730950 | 0.76 | TAAR1 (0.53) | TAAR1GPR52TSHRHPGDSIGMAR1 | |
| SCHEMBL2574637 | 0.76 | MEN1 (0.44) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL20141396 | 0.74 | TAAR1 (0.49) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL4059871 | 0.74 | TAAR1 (0.47) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL1027707 | 0.74 | KMT2A (0.45) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL555604 | 0.73 | TAAR1 (0.62) | TAAR1MEN1KMT2AALDH1A1GPR52 | |
| SCHEMBL1690653 | 0.73 | MEN1 (0.44) | TAAR1MEN1KMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |