Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704199 | 0.92 | TAAR1 (0.55) | TAAR1PTGESRIPK1MEN1KMT2A | |
| SCHEMBL1946468 | 0.83 | MAOA (0.46) | MEN1KMT2AHTTL3MBTL1LMNA | |
| SCHEMBL67173 | 0.82 | RIPK1 (0.56) | TAAR1PTGESRIPK1MEN1KMT2A | |
| SCHEMBL2574637 | 0.82 | MEN1 (0.44) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL3750437 | 0.76 | TAAR1 (0.50) | TAAR1RIPK1SIGMAR1FFAR1FFAR4 | |
| SCHEMBL1026339 | 0.75 | TAAR1 (0.47) | TAAR1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL4158364 | 0.75 | OPRK1 (0.55) | MEN1KMT2AHTTL3MBTL1OPRD1 | |
| SCHEMBL18316992 | 0.75 | TAAR1 (0.65) | TAAR1PTGESRIPK1MEN1KMT2A | |
| SCHEMBL20141439 | 0.74 | TAAR1 (0.46) | TAAR1RIPK1MEN1KMT2AHTT | |
| SCHEMBL1205533 | 0.74 | MAOA (0.49) | MEN1KMT2AHTTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |