Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.67 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.67 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141905 | 0.90 | MTOR (0.63) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20139283 | 0.90 | MTOR (0.63) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20159216 | 0.89 | MTOR (0.81) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20159090 | 0.89 | MTOR (0.71) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20159093 | 0.87 | MTOR (0.68) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20140500 | 0.86 | MTOR (0.67) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20140071 | 0.86 | MTOR (0.78) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20158919 | 0.86 | MTOR (0.72) | MTORRPTORMLST8CHRM4ALDH1A1 | |
| SCHEMBL20158988 | 0.85 | MTOR (0.73) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20139877 | 0.85 | MTOR (0.64) | MTORRPTORMLST8CHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |