Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 7/20 | 0.68 |
| ▸ | RPTOR | Q8N122 | 7/20 | 0.68 |
| ▸ | MLST8 | Q9BVC4 | 7/20 | 0.68 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159090 | 0.92 | MTOR (0.71) | MTORRPTORMLST8TACR3ALDH1A1 | |
| SCHEMBL20159216 | 0.91 | MTOR (0.81) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20142656 | 0.88 | MTOR (0.77) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20142657 | 0.88 | MTOR (0.77) | MTORRPTORMLST8TACR3DRD2 | |
| SCHEMBL20159082 | 0.87 | MTOR (0.75) | MTORRPTORMLST8TACR3ALDH1A1 | |
| SCHEMBL20158988 | 0.87 | MTOR (0.73) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20141504 | 0.87 | MTOR (0.67) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20159217 | 0.86 | MTOR (0.74) | MTORRPTORMLST8TACR3ALDH1A1 | |
| SCHEMBL20140500 | 0.86 | MTOR (0.67) | MTORRPTORMLST8ALDH1A1HTR7 | |
| SCHEMBL20140071 | 0.85 | MTOR (0.78) | MTORRPTORMLST8ALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |