Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 18/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141115 | 0.85 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8437522 | 0.81 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL5214565 | 0.80 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7399910 | 0.80 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL12469312 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7404938 | 0.77 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4438391 | 0.76 | KMT2A (0.36) | SLC6A2SLC6A4SLC6A3KMT2ACYP2D6 | |
| SCHEMBL4439232 | 0.76 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL4051628 | 0.76 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL4436886 | 0.74 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |