Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.38 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL20140845 | 1.00 | CHRM4 (0.45) | CHRM4CHRM1PPARGGRM1MTOR | |
| Trifluoroacetic Acid SCHEMBL20141565 | 1.00 | CHRM4 (0.45) | CHRM4CHRM1PPARGGRM1MTOR | |
| SCHEMBL20140732 | 0.96 | CHRM1 (0.47) | CHRM4CHRM1PPARGGRM1MTOR | |
| SCHEMBL20157507 | 0.96 | CHRM1 (0.47) | CHRM4CHRM1PPARGGRM1MTOR | |
| Trifluoroacetic Acid SCHEMBL20140703 | 0.89 | CHRM4 (0.42) | CHRM4CHRM1PPARGGRM1MTOR | |
| SCHEMBL20157415 | 0.85 | PPARG (0.42) | CHRM1PPARG | |
| SCHEMBL20156856 | 0.85 | MTOR (0.44) | CHRM4CHRM1GRM1MTORRPTOR | |
| SCHEMBL20156876 | 0.85 | MTOR (0.44) | CHRM4CHRM1GRM1MTORRPTOR | |
| SCHEMBL20156877 | 0.85 | MTOR (0.44) | CHRM4CHRM1GRM1MTORRPTOR | |
| SCHEMBL20140054 | 0.85 | CHRM1 (0.42) | CHRM4CHRM1PPARGGRM1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |