Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC27A1 | Q6PCB7 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140732 | 0.89 | CHRM1 (0.47) | PPARGCHRM1 | |
| SCHEMBL20157507 | 0.89 | CHRM1 (0.47) | PPARGCHRM1 | |
| SCHEMBL20157124 | 0.87 | PPARG (0.42) | PPARGCHRM1L3MBTL1ALDH1A1GAA | |
| SCHEMBL20156964 | 0.85 | MTOR (0.49) | PPARGL3MBTL1LMNAKDM4EHTT | |
| Trifluoroacetic Acid SCHEMBL20140845 | 0.85 | CHRM4 (0.45) | PPARGCHRM1 | |
| Trifluoroacetic Acid SCHEMBL20141565 | 0.85 | CHRM4 (0.45) | PPARGCHRM1 | |
| Trifluoroacetic Acid SCHEMBL20141567 | 0.85 | CHRM4 (0.45) | PPARGCHRM1 | |
| SCHEMBL20141707 | 0.83 | MTOR (0.47) | PPARGKDM4EOPRM1OPRK1 | |
| SCHEMBL20156876 | 0.77 | MTOR (0.44) | CHRM1 | |
| SCHEMBL20156877 | 0.77 | MTOR (0.44) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |