Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.54 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.54 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.54 |
| ▸ | NAAA | Q02083 | 8/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141572 | 1.00 | MTOR (0.54) | MTORRPTORMLST8NAAAGRM1 | |
| SCHEMBL20133778 | 0.90 | MTOR (0.60) | MTORRPTORMLST8NAAAGRM1 | |
| SCHEMBL20149740 | 0.82 | MTOR (0.69) | MTORRPTORMLST8 | |
| SCHEMBL20133715 | 0.82 | MTOR (0.70) | MTORRPTORMLST8GRM1AVPR1A | |
| SCHEMBL22187986 | 0.81 | MTOR (0.65) | MTORRPTORMLST8GRM1AVPR1A | |
| SCHEMBL22693226 | 0.79 | MTOR (0.83) | MTORRPTORMLST8GRM1AVPR1A | |
| SCHEMBL20141509 | 0.75 | MTOR (0.54) | MTORRPTORMLST8TRPV1 | |
| SCHEMBL20133747 | 0.75 | MTOR (0.72) | MTORRPTORMLST8 | |
| SCHEMBL20133570 | 0.74 | MTOR (0.61) | MTORRPTORMLST8GRM1HCRTR1 | |
| SCHEMBL20142908 | 0.74 | MTOR (0.61) | MTORRPTORMLST8GRM1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |