Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.61 |
| ▸ | RPTOR | Q8N122 | 9/20 | 0.61 |
| ▸ | MLST8 | Q9BVC4 | 9/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133570 | 1.00 | MTOR (0.61) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20149878 | 0.93 | MTOR (0.57) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20133591 | 0.93 | MTOR (0.57) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20149891 | 0.92 | MTOR (0.67) | MTORRPTORMLST8GPR6MAPT | |
| SCHEMBL20149914 | 0.88 | MTOR (0.52) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20133587 | 0.88 | MTOR (0.52) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20149879 | 0.88 | MTOR (0.58) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20133807 | 0.87 | MTOR (0.52) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20133580 | 0.87 | MTOR (0.64) | MTORRPTORMLST8HCRTR1HCRTR2 | |
| SCHEMBL20133754 | 0.87 | MTOR (0.64) | MTORRPTORMLST8HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |