Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045861 | 1.00 | GRM1 (0.61) | GRM1HDAC1MAP4K4GPR119CHRM4 | |
| SCHEMBL28966496 | 0.87 | HDAC1 (0.58) | HDAC1MAP4K4GPR119CHRM1SLC6A9 | |
| SCHEMBL28966494 | 0.87 | HDAC1 (0.58) | HDAC1MAP4K4GPR119CHRM1SLC6A9 | |
| SCHEMBL28966549 | 0.87 | HDAC1 (0.58) | HDAC1MAP4K4GPR119CHRM1SLC6A9 | |
| SCHEMBL31552986 | 0.86 | HDAC1 (0.60) | GRM1HDAC1MAP4K4GPR119DDB1 | |
| SCHEMBL18822849 | 0.86 | HDAC1 (0.66) | GRM1HDAC1MAP4K4GPR119HDAC3 | |
| SCHEMBL15986821 | 0.86 | HDAC1 (0.66) | GRM1HDAC1MAP4K4GPR119HDAC3 | |
| SCHEMBL30427129 | 0.86 | HDAC1 (0.66) | GRM1HDAC1MAP4K4GPR119HDAC3 | |
| SCHEMBL18149851 | 0.86 | HDAC1 (0.60) | GRM1HDAC1MAP4K4GPR119DDB1 | |
| SCHEMBL30767297 | 0.86 | HDAC1 (0.60) | GRM1HDAC1MAP4K4GPR119DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |