Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18149853 | 1.00 | HDAC1 (0.60) | HDAC1MAP4K4GPR119GRM1AKR1C3 | |
| SCHEMBL18149851 | 1.00 | HDAC1 (0.60) | HDAC1MAP4K4GPR119GRM1AKR1C3 | |
| SCHEMBL30767297 | 1.00 | HDAC1 (0.60) | HDAC1MAP4K4GPR119GRM1AKR1C3 | |
| SCHEMBL31045861 | 0.86 | GRM1 (0.61) | HDAC1MAP4K4GPR119GRM1HDAC3 | |
| SCHEMBL30427129 | 0.86 | HDAC1 (0.66) | HDAC1MAP4K4GPR119GRM1HDAC3 | |
| SCHEMBL18822849 | 0.86 | HDAC1 (0.66) | HDAC1MAP4K4GPR119GRM1HDAC3 | |
| SCHEMBL15986821 | 0.86 | HDAC1 (0.66) | HDAC1MAP4K4GPR119GRM1HDAC3 | |
| SCHEMBL25659873 | 0.86 | HDAC1 (0.66) | HDAC1MAP4K4GPR119GRM1HDAC3 | |
| SCHEMBL20141579 | 0.86 | GRM1 (0.61) | HDAC1MAP4K4GPR119GRM1HDAC3 | |
| SCHEMBL16026429 | 0.85 | HDAC1 (0.67) | HDAC1MAP4K4GPR119GRM1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061035-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2025-03-27 | — | — | WO | disclosed |