Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133852 | 0.89 | MTOR (0.49) | MTORRPTORMLST8DRD3DRD2 | |
| SCHEMBL20129666 | 0.85 | MTOR (0.62) | MTORRPTORMLST8CHEK1CHEK2 | |
| SCHEMBL20133548 | 0.85 | MTOR (0.56) | MTORRPTORMLST8CHEK1CHEK2 | |
| SCHEMBL20133693 | 0.83 | MTOR (0.54) | MTORRPTORMLST8CHEK1CHEK2 | |
| SCHEMBL20133701 | 0.83 | MTOR (0.61) | MTORRPTORMLST8DRD3DRD2 | |
| SCHEMBL20129693 | 0.82 | MTOR (0.61) | MTORRPTORMLST8KDM4EKMT2A | |
| SCHEMBL20141296 | 0.82 | MTOR (0.53) | MTORRPTORMLST8CHEK1CHEK2 | |
| SCHEMBL20133723 | 0.80 | MTOR (0.55) | MTORRPTORMLST8DRD3DRD2 | |
| SCHEMBL20149888 | 0.80 | MTOR (0.51) | MTORRPTORMLST8DRD3DRD2 | |
| SCHEMBL20133856 | 0.79 | MTOR (0.56) | MTORRPTORMLST8CHEK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |