Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133585 | 0.89 | PLD1 (0.41) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL8145266 | 0.80 | SLC6A2 (0.48) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL20140977 | 0.78 | PLD1 (0.43) | PLD1CYP2D6HTR2CHTR2AHTR2B | |
| SCHEMBL6111512 | 0.78 | PLD1 (0.48) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL20129704 | 0.77 | PLD1 (0.50) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL21360320 | 0.75 | PLD1 (0.54) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL21360414 | 0.75 | PLD1 (0.54) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9807138 | 0.72 | PLD1 (0.47) | PLD1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL20141457 | 0.72 | CYP2D6 (0.36) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL31484592 | 0.71 | TAAR1 (0.32) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | PLD1 1370/4885SLC6A2 3251/4885SLC6A4 1595/4885 |
| US-10414727-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | PLD1 1370/4885SLC6A2 3251/4885SLC6A4 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.