Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31045993 | 0.84 | CYP2D6 (0.50) | CYP2D6SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL20133585 | 0.82 | PLD1 (0.41) | CYP2D6SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL20141404 | 0.78 | FPR2 (0.48) | SLC6A2SLC6A4SLC6A3HDAC8HDAC6 | |
| SCHEMBL20140978 | 0.77 | MTOR (0.39) | HDAC8HDAC6 | |
| SCHEMBL20133720 | 0.76 | SLC6A2 (0.40) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20141556 | 0.76 | SLC6A2 (0.40) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21360351 | 0.75 | HDAC8 (0.44) | HDAC8HDAC6 | |
| SCHEMBL15858056 | 0.73 | HTR2C (0.45) | HDAC8HDAC6HDAC1HTR2CKCNH2 | |
| SCHEMBL20142005 | 0.72 | PLD1 (0.39) | CYP2D6SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL30132155 | 0.71 | CYP2D6 (0.35) | CYP2D6SLC6A2SLC6A4SLC6A3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |