Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139933 | 0.86 | CHRM1 (0.44) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20157518 | 0.86 | CHRM1 (0.44) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20140204 | 0.84 | CHRM1 (0.48) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20141104 | 0.79 | CHRM1 (0.46) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20140810 | 0.76 | CHRM1 (0.43) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20157522 | 0.76 | CHRM1 (0.43) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20142114 | 0.76 | CHRM1 (0.42) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20157520 | 0.76 | CHRM1 (0.42) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20141463 | 0.74 | CHRM1 (0.46) | CHRM1GRM1CHRM4CHRM2CHRM3 | |
| SCHEMBL20156867 | 0.72 | CHRM1 (0.45) | CHRM1GRM1CHRM4CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |