Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 11/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139933 | 1.00 | CHRM1 (0.44) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20140204 | 0.90 | CHRM1 (0.48) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20157522 | 0.90 | CHRM1 (0.43) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20140810 | 0.90 | CHRM1 (0.43) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20142114 | 0.90 | CHRM1 (0.42) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20157520 | 0.90 | CHRM1 (0.42) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20142064 | 0.86 | CHRM1 (0.44) | CHRM1CHRM4GRM1HDAC1CHRM2 | |
| SCHEMBL20140682 | 0.83 | CHRM4 (0.44) | CHRM1CHRM4CHRM2PPARG | |
| SCHEMBL20157521 | 0.83 | CHRM4 (0.44) | CHRM1CHRM4CHRM2PPARG | |
| SCHEMBL20157201 | 0.81 | GRM1 (0.41) | CHRM4GRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |