Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319708 | 0.74 | DYRK1B (0.40) | DYRK1ADYRK1B | |
| SCHEMBL8327596 | 0.71 | DYRK1A (0.38) | DYRK1ADYRK1B | |
| SCHEMBL8328800 | 0.71 | DYRK1A (0.52) | DYRK1ADYRK1B | |
| SCHEMBL23199596 | 0.71 | DYRK1B (0.45) | DYRK1ADYRK1B | |
| SCHEMBL15726869 | 0.71 | PIM1 (0.45) | DYRK1ADYRK1B | |
| SCHEMBL1639312 | 0.70 | PIK3CA (0.44) | — | |
| SCHEMBL16516909 | 0.69 | HCAR2 (0.36) | DYRK1ADYRK1B | |
| SCHEMBL1689336 | 0.68 | CCNA2 (0.42) | DYRK1ADYRK1B | |
| SCHEMBL3433362 | 0.67 | DYRK1A (0.33) | DYRK1ADYRK1B | |
| SCHEMBL4779596 | 0.67 | DYRK1A (0.38) | DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089786-A1 | ATG7 INHIBITORS AND THE USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |