Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 19/20 | 0.83 |
| ▸ | CDK2 | P24941 | 19/20 | 0.83 |
| ▸ | GSK3A | P49840 | 1/20 | 0.75 |
| ▸ | GSK3B | P49841 | 1/20 | 0.75 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142463 | 0.91 | GSK3A (0.89) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL5725190 | 0.87 | CCNA2 (0.91) | CCNA2CDK2GSK3AGSK3BCCNE1 | |
| SCHEMBL20142196 | 0.87 | GSK3A (0.81) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL20142068 | 0.86 | GSK3A (1.00) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL20142363 | 0.86 | CCNA2 (0.89) | CCNA2CDK2CCNE1 | |
| SCHEMBL20142449 | 0.86 | GSK3A (0.80) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL20141893 | 0.86 | GSK3A (0.80) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL20142290 | 0.86 | GSK3A (0.80) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL20141891 | 0.86 | GSK3A (0.80) | CCNA2CDK2GSK3AGSK3B | |
| SCHEMBL20142458 | 0.86 | GSK3A (0.80) | CCNA2CDK2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | claimed |
| WO-2018089902-A1 | DIAMINOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | APOGEE BIOTECHNOLOGY CORPORATION (US) | 2018-05-17 | — | — | WO | disclosed |